Sexuality education includes topics such as anatomy, intimate relationships, sexual reproduction, sexually transmitted infections, sexual activity, sexual orientation, gender identity, abstinence, contraception, and reproductive rights and responsibilities. The American Academy of Pediatrics has found that developmentally appropriate, evidence-based education about sexuality and sexual reproduction provided by pediatricians, schools, other professionals, and parents or caregivers is important to help children and adolescents make informed, positive, and safe choices about healthy relationships, responsible sexual activity, and their reproductive health. Sexuality education also helps to prevent adolescent pregnancy, human immunodeficiency virus (HIV), and sexually transmitted infections for children and adolescents. This is especially important for children and youth in out-of-home (OOHC) care who may be at higher risk for early pregnancy, unsafe sexual relationships including trafficking, and engaging in risky behaviors. It is also important that this information is reiterated, appropriate to age, throughout child and adolescent developmental stages.